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Hae accounts for only a small fraction of all cases of angioedema Two new studies presented at the 2025 american college of allergy, asthma and immunology (acaai) annual scientific meeting in orlando shed light on how hereditary angioedema (hae)—a rare. To avoid potentially fatal consequences such as upper airway obstruction and unnecessary abdominal surgery, the importance of a correct diagnosis cannot be overemphasized.

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Hereditary angioedema (hae) is a rare, genetic disorder that causes episodes of swelling in the face, hands, feet and elsewhere While current treatment options may have vastly improved life with hae, many are still impacted by the disease. Symptoms usually begin in childhood.

Our association is a community of people affected by hae and their loved ones who are leading the fight in hae research, advocacy and finding a cure.

Hereditary angioedema is a rare genetic condition that causes swelling under the skin and lining of the gut and lungs It can happen in different parts of your body You are born with hereditary. Hae symptoms include episodes of edema (swelling) in various body parts including the hands, feet, face and airway.

Hereditary angioedema (hae) is a disease characterized by recurrent episodes of angioedema, without urticaria (also called wheals) or pruritus, which most often affect the skin or mucosal tissues of the upper respiratory and gastrointestinal tracts. The symptoms of hereditary angioedema (hae) include recurring swelling in different areas of the body Early signs of an attack may be tingling and a rash, followed by swelling in the affected area Hae attacks can be unpredictable and vary by person.

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The most common cause of hae is a decrease in c1 esterase inhibitor (c1 inh), a protein that is part of our body’s normal immune system

A peptide called bradykinin is thought to be responsible for the hae symptoms of swelling, inflammation and pain. Living with hereditary angioedema (hae) often means living with mild attacks and regular accommodations

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